The aim of this research is to fabricate polycaprolactone (PCL) and polycaprolactone/poly-pyrrole (PCL/PPy) scaffolds by electrospinning method. In order to investigate the effect of electrospinning parameters and concentration of both polycaprolactone and PPy on the morphology, wettability and electrical conductivity of electrospun scaffold the following method is done. Concentrations of PCL and PPy are selected 17, 20, 25%wt and 0, 2.5, 5 and 10%wt respectively. Also, the electrospinning is performed at different voltage (i. e. 12, 14 and 16 kV). The results indicate that increasing the concentration of polycaprolactone has increased the fiber diameter, decreased the number of beads, and changed the morphology of the beads from spherical to spindle-shaped and elongated. The lowest number of beads is observed for all samples at 14 kV voltage. Polycaprolactone scaffold with a concentration of 25%wt and a voltage of 14 kV is selected as the optimal sample and poly-pyrrole particles were added to this sample. By adding poly-pyrrole particles with a concentration of 2.5%wt, the diameter of the fibers increased, and then by increasing the concentration to 5 and 10%wt, the diameter decreased. Due to the hydrophilic nature of poly-pyrrole, increasing its concentration has improved the hydrophilicity of the scaffold. Also, by adding 5%wt of poly-pyrrole particles, the electrical conductivity of polycaprolactone fibers has increased from 1.1 × 10-12 to 4.7 × 10-9 siemens per meter.